Goldy Honorer-Descartes

Goldy Honorer-Descartes, born Shradha Mukherjee. Goldy Honorer-Descartes pen name/nickname/preferred name in honour of my intellectual father René Descartes. The French 'Honorer Descartes', translates to 'Honouring Descartes'.

Call To Action

I am available for on-site, remote, or hybrid positions in science and technology, as a student, staff member, post-doc, intern, consultant, project manager (either for courses or research), including anonymous roles such as an 'anonymous' content creator of video, audio, and written media, and as an 'anonymous' researcher for entire scientific method cycle from hypothesis to product launch (ideation, experimentation, data analysis, result interpretation, grant writing, manuscript writing and clinical trials or other translation avenues), compensated either as an one-time payment, salary, or scholarship. I am interested in pursuing positions in countries that are at the forefront of environmental science, computational biology, neuroscience, oncology, microbiology, nanotechnology and cybersecurity, namely, EU member states, UK, Australia, Canada, New Zealand, and Switzerland, while for hardware, I am specifically interested in Japan and South Korea. Among other tech-science hubs, Loxbridge England, Canada's British Columbia life science hub, Germany's Berlin life science and tech hub, France's Paris life science and tech hub, 'New England' Boston-Cambridge Biotech hub, San Francisco Bay Area 'Silicon Valley' and Shenzhen-Hong Kong-Guangzhou 'Guangdong–Hong Kong–Macao Greater Bay Area', I'm especially interested in Germany's 'Grey City' Berlin, France's 'City of Light' Paris, 'The Pearl of The Orient' and 'London of the East', namely Hong-Kong, Loxbridge (London, Cambridge or Oxford) England, British Columbia Canada and Boston-Cambridge 'New England' US.

About me

What are my accomplishments? (proven merit) My education includes graduate level degrees in chemistry, biochemistry and computation (health informatics). My research publications as first and/or corresponding author (2013-present) are in domains of neuroscience, neurological diseases, cancers, stem cells, neurotoxicity and heavy metal toxicity. These publications utilised techniques of molecular biology, biochemistry, bioinformatics, genomic/omics, statistics, machine learning, AI, natural language processing and network analysis. I have published papers (2013-present) in and reviewed papers (2020-present) for, @Nature https://www.nature.com/siteindex, @FrontiersIn https://www.frontiersin.org/journals and @ElsevierConnect https://www.elsevier.com/products/journals (Cell Press) tier 1 highly cited high impact family of journals in addition to others.

What are my soft skills? (skills that have helped me achieve my proven merit) To put it simply, my soft skills are rooted in my passion for knowledge work. 'Give me problems, give me work, give me the most abstruse cryptogram or the most intricate analysis, and I am in my own proper atmosphere' quote from Sherlock Holmes, The Sign of Four by Sir Arthur Conan Doyle. My research experience has potentiated my ability to plan, problem-solve and perform intricate scientific experiments to unravel novel discoveries. My experience in scientific communication through presentations and publications, has honed my ability to convey complex ideas and technical information in a concise and accessible manner. Taken together, I am confident my proven merit and work ethics, make me an ideal candidate to contribute to your organization's success and create tangible value.

What motivates me? (driving force) The goal is to keep learning because learning has no age limit, infact it is limitless! Learning is an adventure, and "Adventure is worthwhile in itself"-quote by Amelia Earhart ref:https://www.ameliaearhart.com/quotes. My passion is to learn and then apply that learning, wherein the application itself becomes project based learning. Indeed, this learn-and-apply cycle, is both the journey and the destination for me. I hope this learn-and-apply cycle will be sustainable i.e. the learn-and-apply cycle I hope will not only enrich me at an intrinsic level, but also enrich me at an extrinsic (financial) level en route to spiritual independence and financial independence.

This is well captured by two quotes, a) (spiritual independence) "My soul, thou has long been held captive; the hour has now come for thee to quit thy prison, to leave the trammels of this body; suffer then, this separation with joy and courage." -quote last words of René Descartes. ref:https://en.wikipedia.org/wiki/Ren%C3%A9_Descartes and ref:https://archive.philosophersmag.com/philosophers-paris/ b) (financial independence) “I became a journalist because I decided it was more important to do what you’re good at and enjoy than it is to make a lot of money. Because of that decision, and because of all of you who read my work and shared your stories with me, I became one of the richest men in Idaho.”-quote Tim Woodward ref:Idaho Statesman writer Tim Woodward course by Idaho State University, ref: https://woodwardblog.com and ref: Idaho the Movie (2017) | Full Documentary Movie | Idaho Movie I am also motivated to skill up so that I can do best work with the best by acquiring positions in countries that are at the forefront of environmental science, computational biology, neuroscience, oncology, microbiology, nanotechnology and cybersecurity, namely, EU member states, UK, Australia, Canada, New Zealand, and Switzerland, while for hardware, I am specifically interested in Japan and South Korea. Among other tech-science hubs, Loxbridge England, Canada's British Columbia life science hub, Germany's Berlin life science and tech hub, France's Paris life science and tech hub, 'New England' Boston-Cambridge Biotech hub, San Francisco Bay Area 'Silicon Valley' and Shenzhen-Hong Kong-Guangzhou 'Guangdong–Hong Kong–Macao Greater Bay Area', I'm especially interested in Germany's 'Grey City' Berlin, France's 'City of Light' Paris, 'The Pearl of The Orient' and 'London of the East', namely Hong-Kong, Loxbridge (London, Cambridge or Oxford) England, British Columbia Canada and Boston-Cambridge 'New England' US. In UK, France, Germany and US, I am especially drawn to Lake District, Haute-Savoie Department, Bavaria State and 'Gem state' Idaho State, respectively, for their aesthetics and culture, which is conducive to learning and creativity, and is in keeping with Friedrich Schiller's 'Letters on the Aesthetical Education of Man'.

All my motivations and goals are focused on paying thanks, with service and prayers, for some of the debt I owe to the civilized developed world, especially but not limited to England, for the freedom to access and enjoy (all that I love) their knowledge of sciences (natural sciences, tech, energy, AI, digital world) and knowledge of humanities (arts, music, literature, culture, style, movies/tv, cuisine, culture of exploraton/discovery/building/wanderlust and above all Christianity); gift of Christianity is the greatest because without it there is neither 'logos' (logic) nor 'ethos' (character/ethics) that are foundational for science, rationalism/philosophy, creativity/arts, culture, and society, basically without Christianity there is no civilized human society.

What positions am I looking for? I am available for on-site, remote, or hybrid positions in science and technology, as a student, staff member, post-doc, intern, consultant, project manager (either for courses or research), including anonymous roles such as an 'anonymous' content creator of video, audio, and written media, and as an 'anonymous' researcher for entire scientific method cycle from hypothesis to product launch (ideation, experimentation, data analysis, result interpretation, grant writing, manuscript writing and clinical trials or other translation avenues), compensated either as an one-time payment, salary, or scholarship. These positions should preferably be on topics where I have knowledge gaps and greatest interest, namely, in environmental science, cybersecurity, nanotechnology and microbiology. Having said that, I am also interested in research on topics I have previously worked on, namely, cancer, neuroscience (neurodegeneration and neurodevelopment), stem cells/regenerative medicine, health informatics and bioinformatics. I am interested in pursuing positions in countries that are at the forefront of environmental science, computational biology, neuroscience, oncology, microbiology, nanotechnology and cybersecurity, namely, EU member states, UK, Australia, Canada, New Zealand, and Switzerland, while for hardware, I am specifically interested in Japan and South Korea. This collaboration would be mutually beneficial; given my proven track record and results-driven approach to work, I can contribute by developing a translational product in the context of biomedical research to solve 'the bench to bedside problem' or more broadly speaking, preparing a project for product launch (data insights to actionable policies and on-the-ground actions) to solve 'the last mile problem'. In return, I will gain valuable expertise to address any knowledge gaps in my current skill set. Let me explain my knowledge gaps:

1) Environmental science including and not limited to ecology, biodiversity and climate change: Environmental science is a branch of biology that studies the relationships between living organisms and their environment. It encompasses various aspects, including ecology, biodiversity, climate research, and other environmental factors such as geography, geology, climatology, and more. I am interested in acquiring expertise in these areas. Therefore, I would like to explore opportunities that can help me gain this knowledge and experience.

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These closely related fields of study that contribute to our understanding of the complex relationships between living organisms, their environments, and the broader implications for global climate change and biodiversity conservation. All science including environmental science is, in a fundamental sense, data-driven because experimental and observational data collection is integral to scientific method. Science is, by definition, data-driven. So, why use a specific term like 'Data-Driven Environmental Science'? The distinction is not about the presence of data, but about the scale, source, and methods used to handle that data in the modern era. The term 'Data-Driven Environmental Science' is used to describe the new paradigm where the volume and complexity of data are so immense that they require a new set of tools and a shift in mindset—from testing specific hypotheses to also discovering patterns we didn't know to look for. It's not a separate field, but rather the natural evolution of the field to include Big Data and AI. An analogy for this the difference between traditional craftsmanship and modern industrial manufacturing, wherein both create a product, but the tools, scale, and processes are fundamentally different. Ecological monitoring and environmental science now leverage a powerful suite of technologies and data sources to understand planetary processes. This includes satellite remote sensing and LiDAR to track large-scale changes like deforestation and create 3D maps, while GPS telemetry follows animal movements. On the ground, networks of camera traps, acoustic recorders, and environmental sensors automatically collect data, complemented by citizen science platforms that crowdsource vast datasets and genomics that uses environmental DNA to reveal biodiversity. Long-Term Ecological Research (LTER) Networks provide essential, multi-decade datasets for understanding gradual trends. The analysis of this data deluge relies on core methodologies like machine learning, big data analytics, cloud computing, and data fusion. Key techniques include digital twins, statistical modeling for extreme weather attribution, and machine learning for tracking carbon cycles, modeling species distributions, or monitoring ice sheets. In ecology, AI is applied directly, using computer vision to identify species from camera trap images and machine learning to detect illegal activities like deforestation, transforming diverse data into actionable insights. Humans care about environmental science because it helps us understand the interconnectedness of life on Earth and its effects on our planet's health. By studying how different species interact with their environments and each other, we can better predict future changes in ecosystems and develop strategies to mitigate negative impacts on both human societies and natural habitats. Additionally, understanding biodiversity and climate change allows us to make informed decisions about resource management, conservation efforts, and sustainable development practices that will ensure a healthy planet for generations to come.

2) Cybersecurity, Privacy And Digital Sovereignty: Cybersecurity involves multiple layers of defense to protect valuable data and systems. The first line of defense is deterrence through legislation that encourages organizations to adopt better security practices in order to comply with data protection rules and avoid penalties or legal consequences. The second level of cybersecurity involves counter-attack, whereby attackers are tracked and their methods are identified. This proactive approach helps organizations defend against cyber threats by identifying and tracking adversaries, understanding their tactics, and implementing measures to counteract them. I am interested in positions in all these three levels of cybersecurity, at the computation side, legislative side and research support side.

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The third level of cybersecurity focuses on accountability, with legislation deterring data brokers, protecting data from hackers, and stopping big tech acquisition through purchase and investment. Legislative action is important for protecting user data and preventing profiteering. Enforcing deletion policies ensures that collected data cannot be used or sold without proper authorization, which protects users' privacy rights. This also reduces energy and storage requirements associated with storing large amounts of data. Such legislative enforcement promotes sustainability practices by reducing the environmental harm caused by electronic waste production and disposal. Anti-trust laws promote competition among tech companies, minimizing the impact of cyber threats by distributing risks across multiple entities. Additionally, improved digital habits can help wean humans away from the algorithmic quicksand of bigTech products such as social media (‘doom scrolling’ or ‘social media addiction’) reducing the amount of data available for harvesting by bad actors. I am interested in positions in all these three levels of cybersecurity, at the computation side, legislative side and research support side.

3) Microbiology, immunology, and genetic engineering: Over the past decade, microbiology, immunology, and genetic engineering have undergone significant advancements that have transformed our understanding of biological systems. Microbiologists are now able to identify previously unknown microorganisms through rapid genome sequencing technologies, leading to improved diagnostics and novel antimicrobial strategies. Immunologists have developed mRNA-based vaccines with unprecedented speed and efficacy in vaccine design, while genetic engineers have seen exponential growth through the advent of CRISPR-Cas systems for precise editing of genomes. I am interested in acquiring expertise in these areas with hands-on training in microbiology or immunology. Therefore, I would like to explore opportunities that can help me gain this knowledge and experience.

4) Nanotechnology: The interdisciplinary field of nanomedicine chemistry and chemical delivery (pesticides, fertilizers, medicines), not only has the charm of classic pharmaceutical drug development but it also has the potential to solve the problem of targeted drug delivery. This exciting realm at the intersection of chemistry, medicine, and engineering holds immense potential for revolutionizing healthcare, particularly in targeted drug delivery, diagnostics, and therapeutic intervention at the molecular level. I would like to pursue Nanomedicine Chemistry and Drug Delivery towards bridging the knowledge gap I have in this dynamic field, which encompasses advanced concepts in nanomaterial synthesis, drug formulation, biocompatibility, pharmacokinetics, and regulatory affairs.

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The impact of this field is profound, as it promises to address some of the most pressing challenges in modern medicine, such as reducing side effects, improving efficacy, and personalizing treatments. In the context of medicine, many potential chemicals that work great in cell culture in lab, fail in clinical trials because either they do not reach the target organ or because they spread to other non-target organs causing grave side-effects, which outweigh the benefits of the drug at the target organ. Likewise, in the context of agriculture, when pesticides and fertilizers are not localized to the target pest animal and target plant respectively, they can cause health problems in humans either through consumption of the agricultural product or through soil and water polluted by the chemicals. Nanotechnology has the potential to solve both these targeting issues in medicine and agriculture.

References (citations from HRH i.e. His or Her Royal Highness, are not in order of appearance in the text, these are presented first ahead of other citations out of respect for HRH)References

What motivates me? (quotable quotes)

"Dubito Ergo Cogito; Cogito Ergo Sum" (Latin)
"I doubt therefore I think; I think therefore I am" (English)
-quote by René Descartes. Two main books by René Descartes, are a) Meditations on First Philosophy, in which the existence of God and the immortality of the soul are demonstrated (Latin: Meditationes de Prima Philosophia, in qua Dei existentia et animæ immortalitas demonstratur) and b) Discourse on the Method of Rightly Conducting One's Reason and of Seeking Truth in the Sciences (French: Discours de la Méthode pour bien conduire sa raison, et chercher la vérité dans les sciences)
ref: https://www.bbc.co.uk/programmes/p02pdc6n

"The self is a relation that relates to itself....(for Kierjegaard, the self becomes impossible without existence of a divine 'other' who exists outside and beyond the human)" (English)
-quote by Soren Kierkegaard from one of his notable books 'The Sickness Unto Death: A Christian Psychological Exposition for Upbuilding and Awakening'.
ref: Link1 from www.sorenkierkegaard.nl ref: Link2 The Self and the modern debate on Selfhood from Cambridge University ref: Link3 Selflove and Selfhood from Cambridge Universityref: Subjectivity, Irony and the Crisis of Modernity a free course from University of Copenhagen

"Easy to do are things that are bad and harmful to oneself. But exceedingly difficult to do are things that are good and beneficial" (English)
-quote from 'The Dhammapada (The Buddha's Path To Wisdom), Chapter 12, The Self'
ref: https://www.buddhanet.net/e-learning/buddhism/dp12

"(Mr. Trevor) I don’t know how you manage this, Mr. Holmes, but it seems to me that all the detectives of fact and of fancy would be children in your hands. That’s your line of life, sir, and you may take the word of a man who has seen something of the world...(Sherlock Holmes)And that recommendation, with the exaggerated estimate of my ability with which he prefaced it, was, if you will believe me, Watson, it was the very first thing which ever made me feel that a profession might be made out of what had up to that time been the merest hobby."
-quote from 'The Gloria Scott' story from The Memoirs of Sherlock Holmes by Sir Arthur Conan Doyle
ref: The Strand Magazine 1893 https://www.arthur-conan-doyle.com/wiki/The_Adventure_of_the_Gloria_Scott and Project Gutenberghttps://www.gutenberg.org/ebooks/834

"(James Bond) I'm truly sorry to have to dash off like this but there's been a bit of a flap at the office...(Bond Girl) What kind of work do you do anyways? (James Bond) I travel..sort of a liscenced troubleshooter...keep in touch...(Bond Girl) anytime anyplace...(James Bond) another time another place."
-quote from 007 James Bond movie 'Thunderball' 1965, one of the best yet underrated movies of all time.
ref: Wikipedia https://en.wikipedia.org/wiki/Thunderball_(film)

"Standing in the dock at Southampton, Trying to get to Holland or France, The man in the mac said, 'You've got to go back', You know they didn't even give us a chance, Christ you know it ain't easy, You know how hard it can be, The way things are going, They're going to crucify me"
-quote from 'The Ballad Of John And Yoko' song by The Beatles, one of the best and one of the most European songs of all time
ref: Wikipediahttps://en.wikipedia.org/wiki/The_Ballad_of_John_and_Yoko